Global Chemicals Co.,Ltd

Home
Products
About Us
Factory Tour
Quality Control
Contact Us
Request A Quote
Home ProductsHgh Human Growth Hormone

Lyophilized Powder GDF-8 1mg/vial Myostatin Human Growth Peptides for Bodybuilding

i tried the 5f-sgt 151 , that was prety good product, and 2g free sample to me for the frist order, will deal with smions for long time business

—— james

the eutylone is very prety good stuff . try them

—— john

good price great product! I love it

—— Adam

I like 5fmdmb, Great supplier!

—— Ethan

not so bad , something wrong happened first , but had a good solve

—— Fdalis

i really enjoy sgt 151 in Au, thanks for smions help. will do more business with him

—— James

a great shopping experience

—— Fdelis

I'm Online Chat Now

Lyophilized Powder GDF-8 1mg/vial Myostatin Human Growth Peptides for Bodybuilding

China Lyophilized Powder GDF-8 1mg/vial Myostatin Human Growth Peptides for Bodybuilding supplier
Lyophilized Powder GDF-8 1mg/vial Myostatin Human Growth Peptides for Bodybuilding supplier Lyophilized Powder GDF-8 1mg/vial Myostatin Human Growth Peptides for Bodybuilding supplier

Large Image :  Lyophilized Powder GDF-8 1mg/vial Myostatin Human Growth Peptides for Bodybuilding

Product Details:

Place of Origin: china
Brand Name: Jintropin
Certification: Jintropin
Model Number: Jintropin

Payment & Shipping Terms:

Minimum Order Quantity: 1vial
Price: Negotiable
Packaging Details: Aluminum foil bag
Delivery Time: 3-5 days after received your deposit
Payment Terms: MoneyGram, Western Union, T/T
Supply Ability: 1000kg/month
Contact Now
Detailed Product Description
Name: Jintropin Purity: 99%
Color: White Delivery Time: 1-2days
Email: Danielsaleschem@gmail.com

Lyophilized Powder GDF-8 1mg/vial Myostatin Human Growth Peptides for Bodybuilding

 

Quick Detail :

 

Product name: GDF-8 (Growth Differentiation Factor 8 Myostatin)
Purity: 85%
Specification: 1mg
Storage:2-8 degree centigrade refrigerator
Package: 10 Vials/Kit
Deliver:1 working day for ready goods,7 days to your destination.
Pacakge:1kit=10vials Alumnium foil+bubble+carton
Customized:accepted.
Country of Origin: China

 

Lyophilized Powder GDF-8 1mg/vial Myostatin Human Growth Peptides for BodybuildingDescription :

Myostatin (GDF-8) is a member of the transforming growth factor-beta (TGF-beta) superfamily that is highly expressed in skeletal muscle, and myostatin loss-of-function leads to doubling of skeletal muscle mass. Myostatin-deficient mice have been used as a model for studying muscle-bone interactions, and here we review the skeletal phenotype associated with altered myostatin signaling. It is now known that myostatin is a key regulator of mesenchymal stem cell proliferation and differentiation, and mice lacking the myostatin gene show decreased body fat and a generalized increase in bone density and strength.

The increase in bone density is observed in most anatomical regions, including the limbs, spine, and jaw, and myostatin inhibitors have been observed to significantly increase bone formation. Myostatin is also expressed in the early phases of fracture healing, and myostatin deficiency leads to increased fracture callus size and strength. Together, these data suggest that myostatin has direct effects on the proliferation and differentiation of osteoprogenitor cells, and that myostatin antagonists and inhibitors are likely to enhance both muscle mass and bone strength.

 

Discovery and sequencing :

GDF-8 / Myostatin Myostatin ,The gene encoding myostatin was discovered in 1997 by geneticists Se-Jin Lee and Alexandra McPherron who produced a strain of mutant mice that lack the gene. These myostatin "knockout" mice have approximately twice as much muscle as normal mice. These mice were subsequently named "mighty mice".


Naturally occurring deficiencies of myostatin have been identified in cattle by Ravi Kambadur, whippets, and humans; in each case the result is a dramatic increase in muscle mass. A mutation in the 3' UTR of the myostatin gene in Texel sheep creates target sites for the microRNAs miR-1 and miR-206. This is likely to cause the muscular phenotype of this breed of sheep.

 

COA :

Item Specification Result
Appearance White powder Complies
Identification Positive Complies
Assay 99.0% min 99. 3%
Loss on Drying 6.0%max. 4.80%
Mass Balance 95.0~105.0% Complies
Acetate Content (HPIC) 12.0%max. 10.80%
Peptide Content (N%) 80.0%min. 88.00%
Amino Acid Composition ±10% of theoretical Complies
Single Impurity (HPLC) 1.0%max. 0.85%
 

Application :

The gene encoding myostatin was discovered in 1997 by geneticists Se-Jin Lee and Alexandra McPherron who produced a strain of mutant mice that lack the gene. These myostatin "knockout" mice have approximately twice as much muscle as normal mice. These mice were subsequently named "mighty mice".

Naturally occurring deficiencies of myostatin have been identified in cattle by Ravi Kambadur, whippets, and humans; in each case the result is a dramatic increase in muscle mass. A mutation in the 3' UTR of the myostatin gene in Texel sheep creates target sites for the microRNAs miR-1 and miR-206. This is likely to cause the muscular phenotype of this breed of sheep.

Human myostatin consists of two identical subunits, each consisting of 109 (NCBI database claims human myostatin is 375 residues long) amino acid residues. Its total molecular weight is 25.0 kDa. The protein is inactive until a protease cleaves the NH2-terminal, or "pro-domain" portion of the molecule, resulting in the active COOH-terminal dimer. Myostatin binds to the activin type II receptor, resulting in a recruitment of either coreceptor Alk-3 or Alk-4. This coreceptor then initiates a cell signaling cascade in the muscle, which includes the activation of transcription factors in the SMAD family - SMAD2 and SMAD3. {{|}}These factors then induce myostatin-specific gene regulation. When applied to myoblasts, myostatin inhibits their differentiation into mature muscle fibers.


Myostatin also inhibits Akt, a kinase that is sufficient to cause muscle hypertrophy, in part through the activation of protein synthesis. However, Akt is not responsible for all of the observed muscle hyperthrophic effects which are mediated by myostatin inhibition[8] Thus myostatin acts in two ways: by inhibiting muscle differentiation, and by inhibiting Akt-induced protein synthesis.

Lyophilized Powder GDF-8 1mg/vial Myostatin Human Growth Peptides for Bodybuilding

Related peptide products :

 
Peptide Specification Peptide specification
MGF 2mg/vial Ipamorelin 2mg/vial
PEG MGF 2mg/vial Hexarelin 2mg/vial
CJC-1295 with DAC 2mg/vial Sermorelin 2mg/vial
CJC-1295 without DAC 2mg/vial Oxytocin 2mg/vial
PT-141 10mg/vial TB500 2mg/vial
Melanotan I 10mg/vial pentadecapeptide BPC 157 2mg/vial
Melanotan II 10mg/vial Fragment 176-191 2mg/vial
GHRP-2 5mg or 10mg/vial Triptorelin 2mg/vial
GHRP-6 5mg or 10mg/vial Tesamorelin 2mg/vial
Gonadorelin 2mg or 10mg/vial AOD-9604 2mg/vial
DSIP 2mg/vial Follistatin 344 1mg/vial
Selank 5mg/vial SNAP-8 Customized
 

How to proceed steroid order?

 

First: Please let me know the itmes you are looking for, quantity, and the destination country
.

Second: You confirm all details, and offer us purchasing order;

 

Third: We send the detail price of our product and offer suitable shipping method reference.

 

Forth: You confirm the order and pay money 100% in advance and send us detail address.

 

Fifth: We arrange the shipment according to your requirements.

 

Sixth: We offer after-sales service after you receive parcel;

 

Our Advantages :


1. Packing
Professional packing with professional materials, and We'll give clients several Packing way to choose after you contact me through my email.


2. Quality
Our company is a professional leading factory in China in pharmaceutical area, ach batch of steroid powders have to tested by our QC(quality control) department before they are allowed to sell.


3. Delivery
We can pack your powders within 48 hours after your payment, and corresponding picture of your powders' parcel will be sent to you.


4. Price
Best prices you're sure to be satisfied, the more you buy, the more competitive prices you get.


5. Payment
T/T, paypal, Money Gram,Bitcoin, Western Union

 


Product Tags:

muscle growth peptides

human growth hormone powder

Lyophilized Powder GDF-8 1mg/vial Myostatin Human Growth Peptides for Bodybuilding

Contact Details
Global chemicals Co.,Ltd

Contact Person: smions

Tel: +8615563263311

Send your inquiry directly to us (0 / 3000)